Macrophages in the Human Body : A Tissue Level Approach – Ebook Instant Download/Delivery ISBN(s): 9780128213858,012821385X
Product details:
- ISBN-10 : 012821385X
- ISBN-13 : 978-0128213858
- Author: Dr. Niels Olson Sairava Camara
Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions.
Table contents:
Chapter 1: Macrophages: From Metchnikoff to 2020 and ahead
Chapter 2: Macrophage differentiation
Chapter 3: Metabolic requirement for macrophages
Chapter 4: Spleen, lymph nodes, and lymphoid tissues—Inflammatory syst
Chapter 5: Kidney—Inflammation and remodeling
Chapter 6: Dermal macrophages in health and disease
Chapter 7: Bone—From macrophage to osteoclast and osteolytic diseases
Chapter 8: Microglia and border-associated macrophages in the central
Chapter 9: Intestines—Inflammatory and digestive system
Chapter 10: Lungs—Inflammatory and respiratory system
Chapter 11: Macrophages in the immune-endocrine milieu of reproductive tis
Chapter 12: Macrophages at the maternal-fetal interface
Chapter 13: Targeting macrophages in systemic diseases
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