Molecular, Cellular, and Metabolic Fundamentals of Human Aging Evandro 1st Edition Fei Fang & Linda Hildegard Bergersen & Brian C. Gilmour

Molecular, Cellular, and Metabolic Fundamentals of Human Aging Evandro 1st Edition Fei Fang & Linda Hildegard Bergersen & Brian C. Gilmour- Ebook Instant Download/Delivery ISBN(s): 9780323916172,0323916171,9780323916189, 032391618X

Product details:

• ISBN 10: 032391618X
• ISBN 13: 9780323916189
• Author:Fei Fang , Linda Hildegard Bergersen , Brian C. Gilmour

Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, mitochondrial dysfunction, the impact of decreased ability of autophagosomes and autophagosomes, cellular senescence, changes to communication molecules, and the impact of stem cell exhaustion.

 

Table contents:

1. Decoding the mystery of ageing and the hallmarks of ageing

Section I. The Genome

2. Epigenetic ageing and its reversal

Section II. Metabolism, Homeostasis and Communication

3. Nutrient sensing and aging

4. Dysregulated proteostasis

Section III. Autophagy and Bioenergetics

5. Autophagy and bioenergetics in aging

Section IV. Senescence

6. Senescence in Ageing

Section V. Applications

7. Ageing and the immune system

8. Canonical and novel strategies to delay or reverse ageing

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