Pan-genomics: Applications, Challenges, and Future Prospects 1st edition by Debmalya Barh, Siomar C. Soares, Sandeep Tiwari – Ebook PDF Instant Download/DeliveryISBN: 9780128170779, 0128170778
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ISBN-10 : 0128170778
ISBN-13 : 9780128170779
Author: Debmalya Barh, Siomar C. Soares, Sandeep Tiwari
Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an “overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics, thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics, encompasses the developments on omics studies to be applied on bacteria related studies.
Pan-genomics: Applications, Challenges, and Future Prospects 1st Table of contents:
Chapter 1: Pan-omics focused to Crick’s central dogma
Abstract
1 Introduction
2 Applications of Pan-genomics in Bacteria
3 Pan-genomics of virus and its applications
4 Pan-genomics of plants and its applications
5 Genomics of algae and its applications
6 Pan-metagenomics and human microbiome
7 Pan-proteomics and its applications
8 Pan-transcriptomics and its applications
9 Pan-cancer analysis and its applications
10 Conclusions
Chapter 2: Bioinformatics approaches applied in pan-genomics and their challenges
Abstract
1 Introduction
2 Pan-genome analysis
3 Challenges
4 Conclusion and future direction
Chapter 3: Evolutionary pan-genomics and applications
Abstract
1 Introduction
2 Computational methods in evolutionary pan-genomics
3 Evolutionary pan-genomics of prokaryotes
4 Evolutionary pan-genomics of eukaryotes
5 Orthology prediction and genomic plasticity in pan-genomics
6 Phylogenomics and genomic epidemiology in pan-genomics
7 Future directions
8 Conclusion
Chapter 4: Insights into old and new foes: Pan-genomics of Corynebacterium diphtheriae and Corynebacterium ulcerans
Abstract
1 Corynebacterium diphtheriae and Corynebacterium ulcerans
2 Phenotypic and genotypic separation of strains—A historical retrospective
3 Beginning of the genome era
4 Pan-genomics of C. diphtheriae
5 Genomics of C. ulcerans
6 Toxin variation and diphtheria toxoid vaccine
7 Conclusions and future directions
Chapter 5: Pan-genomics of veterinary pathogens and its applications
Abstract
1 Introduction
2 Pan-genomics studies of pathogenic bacteria causing veterinary and zoonotic diseases
3 Conclusions
Chapter 6: Pan-genomics of plant pathogens and its applications
Abstract
1 Introduction
2 Pan-genomics of plant pathogens
3 Applications of plant pathogen’s pan-genomics
4 Analyzing pan-genomes
5 Conclusions and future directions
Chapter 7: Pan-genomics of food pathogens and its applications
Abstract
1 Introduction
2 Pan-genomics of E. coli
3 Pan-genomics of Salmonella enterica
4 Pan-genomics of Clostridium spp.
5 Pan-genomics of L. monocytogenes
6 Pan-genomics of S. aureus
7 Conclusions and future directives
Chapter 8: Pan-genomics of aquatic animal pathogens and its applications
Abstract
1 Genome study of aquaculture pathogens
2 Using the comparative pan-genome to analyze aquatic pathogenic bacteria
3 Conclusions and the avenues of pan-genome for analyzing aquatic pathogens
Chapter 9: Pan-genomics of model bacteria and their outcomes
Abstract
1 Introduction
2 Technical approaches and their outcomes
3 Pan-genomics of model bacteria
4 Conclusion
Chapter 10: Pan-genomics of multidrug-resistant human pathogenic bacteria and their resistome
Abstract
Acknowledgment
Conflict of interest
1 Introduction
2 The pan-genomics of human pathogens
3 The pan-genome of resistant bacteria
4 The pan-genome of emergent resistant bacteria
5 PATRIC and other databases
6 Core and accessory genomes of antibiotic-resistant bacteria
7 Pan-genome and resistome
8 New challenges of pan-genome strategy
9 Conclusion
Chapter 11: Pan-genomics of virus and its applications
Abstract
1 Next-generation sequencing strategies
2 Genomic surveillance
3 Genomic epidemiology
4 Bioinformatic tools
5 Conclusions
Chapter 12: Pan-genomics of fungi and its applications
Abstract
1 Introduction
2 Application of pan-genomics of fungi based on meta-analysis
3 Conclusions and future prospective
Chapter 13: Genomics of algae: Its challenges and applications
Abstract
1 Diversity in algae and their evolutionary insights
2 Advancements in genomics and its importance to ecologists
3 Ecological and economic importance of algae
4 Genomics of microalgae
5 Genomics of macroalgae
6 Conclusions
Chapter 14: Pan-genomics of plants and its applications
Abstract
1 Plant pan-genome concept
2 Structure and dynamics of plant pan-genome
3 Plant pan-genome studies
4 Plant pan-genome analysis tools
5 Applications of plant pan-genomics
6 Conclusions and future directions
Chapter 15: Pan-cancer analysis and applications
Abstract
1 Introduction
2 Methods in pan-cancer analysis
3 Pan-cancer analysis findings and applications
4 Limitations of analysis
5 Future prospects
6 Summary
Chapter 16: Reverse vaccinology and drug target identification through pan-genomics
Abstract
1 Introduction and goals of pan-genomics and reverse vaccinology
2 Outcomes of pan-genomics and RV
3 Core genome as the basis of the novel and broad-spectrum drugs and vaccine candidates
4 Pan-genomics
5 Reverse vaccinology
6 Limitations of RV and pan-genomics
7 Future prospects
Chapter 17: Pan-metagenomics: An overview of the human microbiome
Abstract
17.1 Introduction
17.2 Gut pan-metagenome
17.3 Pan-microbiome and its built environment
17.4 Pan-microbiome in pharmacokinetic studies
17.5 The large-scale microbiome projects
17.6 Conclusion
Chapter 18: Pan-transcriptomics and its applications
Abstract
1 Introduction
2 Methodologies in transcriptomics
3 Computational framework of pan-transcriptomics
4 Prokaryotic data analysis software
5 Eukaryotic data analysis software
6 Applications
7 Prokaryotic examples
8 Eukaryotic examples
9 Conclusion and future prospects
Chapter 19: Pan-proteomics: Technologies, applications, and challenges
Abstract
1 Introduction
2 Pan-proteomics concept and proteomics technologies used in pan-proteomics
3 Bioinformatics strategies/tools used in proteomics
4 Pan-proteomics applications and outcomes in microbes
5 Pan-proteomics applications and outcomes in plants
6 Pan-proteomics applications and outcomes in animals
7 Conclusions and future prospective
Chapter 20: Pan-metabolomics and its applications
Abstract
1 Introduction
2 Methodologies of pan-metabolomics
3 Application of pan-metabolomics
4 Development of pan-metabolomics in the future
Chapter 21: Pan-interactomics and its applications
Abstract
1 Introduction
2 Computational analysis of interactome
3 Databases and its types
4 In vivo pan-interactome mapping
5 Applications
6 Conclusions and future perspectives
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