A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery 5th Edition Terry P. Kenakin

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery – Ebook Instant Download/Delivery ISBN(s): 9780128139578,0128139579

Product details:

• ISBN-10 ‏ : ‎ 0128139579
• ISBN-13 ‏ : ‎ 978-0128139578
• Author(s): Terry P. Kenakin

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more.

With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research.

Table contents:

1. What Is Pharmacology?

2. How Different Tissues Process Drug Response

3. Drug-Receptor Theory

4. Pharmacological Assay Formats: Binding

5. Agonists: The Measurement of Affinity and Efficacy in Functional Assays

6. Orthosteric Drug Antagonism

7. Allosteric Modulation

8. The Optimal Design of Pharmacological Experiments

9. Pharmacokinetics

10. Safety Pharmacology

11. The Drug Discovery Process

12. Statistics and Experimental Design

13. Selected Pharmacological Methods

14. Exercises in Pharmacodynamics and Pharmacokinetics

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