A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 6th Edition Terry Kenakin

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 6th Edition Terry Kenakin – Ebook Instant Download/Delivery ISBN(s): 9780323992893,0323992897,9780323992909, 0323992900

Product details:

• ISBN 10: 0323992900
• ISBN 13: 9780323992909
• Author:Terry Kenakin

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets.

Table contents:

Chapter 1. What is pharmacology?

Chapter 2. How different tissues process drug response

Chapter 3. Drug–receptor theory

Chapter 4. Pharmacological assay formats: binding

Chapter 5. Drug targets and drug-target molecules

Chapter 6. Agonists: the measurement of affinity and efficacy in functional assays

Chapter 7. Orthosteric drug antagonism

Chapter 8. Allosteric modulation

Chapter 9. The optimal design of pharmacological experiments

Chapter 10. Pharmacokinetics

Chapter 11. Safety pharmacology

Chapter 12. The drug-discovery process

Chapter 13. Selected pharmacological methods

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