Advances in Protein Chemistry and Structural Biology Volume 115 – DNA Repair – Ebook Instant Download/Delivery ISBN(s): 9780128155592,0128155590,9780128155608, 0128155604

Product details:

• ISBN-10: 0128155604
• ISBN-13: 9780128155608
• Author: Rossen Donev

DNA Repair, Volume 115, the latest release in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more.

Table contents:

Chapter One: DNA repair by photolyases

Chapter Two: TFIIH: A multi-subunit complex at the cross-roads of transcription and DNA repair

Chapter Three: Chromatin control in double strand break repair

Chapter Four: Controlling the balance between chromosome break repair pathways

Chapter Five: Targeting DNA repair in precision medicine

Chapter Six: Replication stress: Driver and therapeutic target in genomically instable cancers

Chapter Seven: Claspin: From replication stress and DNA damage responses to cancer therapy

Chapter Eight: cAMP-mediated regulation of melanocyte genomic instability: A melanoma-preventive strategy

Chapter Nine: Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling

Chapter Ten: Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach

Chapter Eleven: A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase

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