Alpha-glucosidase Inhibitors: Clinically Promising Candidates for Anti-diabetic Drug Discovery 1st Editio Usman Ghani

Alpha-glucosidase Inhibitors: Clinically Promising Candidates for Anti-diabetic Drug Discovery – Ebook Instant Download/Delivery ISBN(s): 9780081027790,0081027796

Product details:

• ISBN-10 ‏ : ‎ 0081027796
• ISBN-13 ‏ : ‎ 978-0081027790
• Author(s): Usman Ghani

Alpha-glucosidase Inhibitors: Clinically Promising Candidates for Anti-diabetic Drug Discovery presents information that researchers can use to address a whole host of promising leads for the development of novel, oral, anti-diabetic drugs with improved efficacy and fewer side effects. Beginning with a discussion of the huge potential of a -glucosidase inhibitor leads and adaptations, and highlighting their importance within the field of anti-diabetic drug discovery, the book provides chemical structures, detailed background information and in vivo and in vitro biological activity data, and more economical adaptations of these structures.

Drawing on the author’s expert research in the field, this book highlights promising leads for development and helps researchers select the most appropriate inhibitors for their own work. It is a useful tool not only for anti-diabetic drug development researchers, but also for those whose research may be enhanced by an understanding of a -glucosidase inhibitor chemistry and activity.

Table contents:

Chapter one. Introduction, rationale and the current clinical status of oral α-glucosidase inhibitors
Chapter two. Natural and synthetic sugar mimics
Chapter three. Polyphenols
Chapter four. Terpenoids and steroids
Chapter five. Azoles and related derivatives
Chapter six. Cyclitols and miscellaneous inhibitors
Chapter seven. Computational and structural biology of α-glucosidase-inhibitor complexes: clues to drug optimization and development
Appendix. A comprehensive list of promising α-glucosidase inhibitors with the activity data discussed in the book
Index

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