Breast Pathology 2nd Edition by David Dabbs 0323462367 9780323462365

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ISBN-10 :  0323462367 

ISBN-13 : 9780323462365

Author : David J Dabbs 

Now completely updated with the latest classifications of breast pathology and molecular diagnosis, David J. Dabbs’ Breast Pathology, 2nd Edition, remains your go-to source for integrated, comprehensive coverage of this fast-changing field. Written by internationally acclaimed pathologists, this definitive reference incorporates genomic and molecular information, clinical presentation, gross and microscopic pathologic findings, radiologic and laboratory diagnosis, immunohistochemistry, and theranostics – providing complete, authoritative information for pathology trainees, practitioners, and oncologists.

Breast Pathology 2nd Table of contents:

1. Normal Breast and Developmental Disorders
Normal Breast
Developmental Disorders
Summary
2. Reactive and Inflammatory Conditions of the Breast
Mammary Duct Ectasia
Fat Necrosis
Granulomatous Lobular Mastitis
Sclerosing Lymphocytic Lobulitis
Breast Infarction
Nodular Fasciitis of the Breast
Systemic Disease in Breast Parenchyma
Summary
3. Infections of the Breast
Lactating Breast Infection
Nonlactating Breast Infection
Zuska (SMOLDering) Breast Disease
Miscellaneous Breast Infections
Summary
4. Epidemiology of Breast Cancer and Pathology of Heritable Breast Cancer
Risk Factors for Breast Cancer
Summary
5. Patient Safety in Breast Pathology
Changing Role of Pathologists in Breast Cancer Diagnosis and Management
Current Challenges in the Practice of Breast Pathology
Mechanisms to Minimize Errors in Breast Pathology
Implementation of Patient Safety-Centered Breast Pathology in Practice
Summary
6. Gross Examination of Breast Specimens
General Principles for Gross Examination of Breast Specimens
Percutaneous Core Needle Biopsies
Recommendations for Handling and Processing of Breast Core Needle Biopsies
Surgical Excisions/Lumpectomies
Separately Submitted Margins and Re-Excision Specimens
Mastectomies
Pitfalls in the Evaluation of Excisions and Mastectomies
Axillary Lymph Nodes
Examination of Breast Prostheses (Implants)
Fresh Tissue Collection for Research and Clinical Purposes
7. Sentinel Lymph Node Biopsy
Clinical Parameters and Feasibility Issues
Predictors of Sentinel Node Metastasis
Pathologic Evaluation
American Joint Committee on Cancer Staging of Sentinel Nodes
Controversial Issues with Regard to Histologic Assessment
Histologic Pitfalls
Predictors of Nonsentinel Involvement
Critical Issues
Summary
8. Breast Imaging Modalities for Pathologists
Mammography
Ultrasound
Magnetic Resonance Imaging
Molecular Breast Imaging
Positron Emission Tomography/Computed Tomography
Sentinel Lymph Node Imaging
Methods for Obtaining, Marking, and Localizing a Tissue Sample
New Methods on The Horizon
Summary
9. Predictive and Prognostic Marker Testing in Breast Pathology: Immunophenotypic Subclasses of Disease
Hormone Receptors in Breast Carcinoma
HER2 Oncogene in Breast Carcinoma
Other Prognostic/Predictive Markers
Summary
10. Molecular-Based Testing in Breast Disease for Therapeutic Decisions
Gene Expression Profiling Using Microarray Technology and Real-Time Reverse Transcription Polymerase Chain Reaction
Prognostic and Predictive Gene Expression Signatures
Other Gene Expression Signatures
MicroRNAs in Breast Cancer
Circulating Tumor Cells
Summary
11. Diagnostic Immunohistology of the Breast
Assessment of Stromal Invasion
Immunohistochemistry of Papillary Lesions
Proliferative Ductal Epithelial Lesions and In Situ Carcinomas
Tumor Type Identification by Immunohistochemistry
Paget Disease of the Breast
Detection of Lymphatic Space Invasion
Sentinel Lymph Node Examination
Systemic Metastasis of Breast Carcinoma
Fibroepithelial Tumors
12. Fibroepithelial Lesions
Fibroadenoma
Phyllodes Tumor
Summary
13. Papilloma and Papillary Lesions
Papilloma
Summary
14. Adenosis and Microglandular Adenosis
Adenosis
Microglandular Adenosis
Summary
15. Nipple Adenoma (Florid Papillomatosis of the Nipple)
Normal Nipple Anatomy
Nipple Adenoma
Summary
16. Radial Scar
Radial Scar
Summary
17. Myoepithelial Lesions of the Breast
Adenomyoepithelioma
Myofibroblastoma
Adenoid Cystic Carcinoma
Pleomorphic Adenoma
Summary
18. Fibrocystic Change and Usual Epithelial Hyperplasia of Ductal Type
Fibrocystic Change
Usual Ductal Hyperplasia
Summary
19. Columnar Cell Alterations, Flat Epithelial Atypia, and Atypical Ductal Epithelial Hyperplasia
Columnar Cell Alterations and Flat Epithelial Atypia
Immunohistology of Columnar Cell–Related Lesions
Relationships Among Flat Epithelial Atypia, Lobular Neoplasia, Atypical Ductal Epithelial Hyperplasia, Low-Grade Ductal Carcinoma In Situ, and Carcinoma: A Molecular Kinship
Summary
20. Molecular Classification of Breast Carcinoma
Intrinsic Gene Set Based Molecular Classification
Other Molecular Subtypes
Molecular Analyses of Special Subtype Carcinomas
Molecular Profiling of Metastatic Disease
Other Multigene Prediction Assays
Immunohistochemical Surrogates to Molecular Classes
Future of Molecular Testing
Summary
21. Lobular Neoplasia and Invasive Lobular Carcinoma
Lobular Carcinoma In Situ and Atypical Lobular Hyperplasia
Invasive Lobular Carcinoma
Molecular Pathology of Lobular Carcinoma
Summary
22. Ductal Carcinoma In Situ
Ductal Carcinoma In Situ
Summary
23. Invasive Ductal Carcinoma of No Special Type and Histologic Grade
Invasive Carcinoma of No Special Type (Ductal NST)
Differential Diagnosis
Summary
24. Triple-Negative and Basal-like Carcinoma
Breast Cancer Molecular Taxonomy
Basal-like Breast Cancer
Summary
25. Metaplastic Breast Carcinoma
Metaplastic Carcinoma
Differential Diagnoses
Summary
26. Apocrine Carcinoma of the Breast
Apocrine Carcinoma of the Breast
27. Paget Disease of the Breast
Epidemiology
Pathogenesis
Clinical Presentation
Clinical Imaging and Diagnosis
Macroscopic Pathology
Microscopic Pathology
Histologic Variants
Cytology
Immunohistochemistry
Differential Diagnosis
Cytogenetics
Treatment and Prognosis
Summary
28. Pathology of Neoadjuvant Therapeutic Response of Breast Carcinoma
Predictors of Therapeutic Response
Evaluation of Therapeutic Response
Posttreatment Prognostic and Predictive Factors
Systems for Evaluating Degree of Response
Reporting of Posttreatment Specimen
Summary
29. Special Types of Invasive Breast Carcinoma: Tubular Carcinoma, Mucinous Carcinoma, Cribriform Carcinoma, Micropapillary Carcinoma, Carcinoma with Medullary Features
Tubular Carcinoma
Invasive Cribriform Carcinoma
Mucinous Carcinoma
Invasive Micropapillary Carcinoma
Medullary Carcinoma
30. Rare Breast Carcinomas: Adenoid Cystic Carcinoma, Neuroendocrine Carcinoma, Secretory Carcinoma, Carcinoma with Osteoclast-like Giant Cells, Lipid-Rich Carcinoma, and Glycogen-Rich Clear Cell Carcinoma
Adenoid Cystic Carcinoma
Neuroendocrine Carcinoma
Secretory Carcinoma
Carcinoma with Osteoclast-like Giant Cells
Lipid-Rich Carcinoma
Glycogen-Rich Clear Cell Carcinoma
Summary
31. Mesenchymal Neoplasms of the Breast
Hamartoma (Adenolipoma, Chondrolipoma, and Myoid Hamartoma)
Hibernoma
Benign Vascular Lesions
Malignant Vascular Tumors
Myofibroblastic Proliferations
Leiomyomatous Lesions
Other Sarcomas
Miscellaneous Benign Mesenchymal Tumors
Summary
32. Neoplasia of the Male Breast
Embryogenesis and Puberty
Benign Proliferative Lesions
Benign Papillary Lesions
Fibroepithelial Lesions
Gynecomastia
Other Benign Disorders of the Male Breast
Carcinoma of the Male Breast
Summary
33. Breast Tumors in Children and Adolescents
Juvenile Papillomatosis
Papillary Duct Hyperplasia (Papilloma, Papillomatosis)
Fibroepithelial Tumors
Atypical Ductal Hyperplasia
Carcinoma
Other Malignant Tumors
Summary
34. Tumors of the Mammary Skin
Benign Skin Tumors of the Surface Epithelium
Surface Carcinomas of the Mammary Skin
Mammary Paget Disease
Nonvascular Cutaneous Mesenchymal Lesions of the Mammary Skin
Benign Cutaneous Vascular and Perivascular Tumors of the Breast
Melanocytic Lesions of the Mammary Skin
Hematopoietic Tumors of the Mammary Skin
Metastatic Tumors of the Mammary Skin
Summary
35. Hematopoietic Tumors of the Breast
Non-Hodgkin Lymphoma
Other Non-Hodgkin Lymphomas
Plasmacytic Neoplasms
Hodgkin Lymphoma
Myeloid Neoplasms and Extramedullary Hematopoiesis
Histiocytic/Dendritic Cell Proliferations
Summary
36. Metastatic Tumors in the Breast
Metastatic Tumors in the Breast
Summary
37. Next-Generation DNA Sequencing and the Management of Patients with Clinically Advanced Breast Cancer
History of DNA Sequencing and the Human Genome
DNA Sequencing Technologies
Comparison of Traditional and Next-Generation Sequencing Strategies for Cancer Cell Genomic Sequencing
Challenges for Delivering Next-Generation Sequencing Results for Cancer Patients
Next-Generation Sequencing in the Management of Clinically Advanced Breast Cancer

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Tags: Breast Pathology, David Dabbs, classifications, molecular diagnosis