Cardio Hepatology Connections Between Hepatic and Cardiovascular Disease 1st Edition by Tatsunori Taniguchi, Samuel Lee – Ebook PDF Instant Download/Delivery: 9780128173954, 0128173955
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• ISBN 10:0128173955
• ISBN 13:9780128173954
• Author:Tatsunori Taniguchi, Samuel Lee
Cardio-Hepatology
Connections Between Hepatic and Cardiovascular Disease
Cardio-Hepatology: Connections Between Hepatic and Cardiovascular Disease provides a direct relationship between the cardiac and hepatic pathologies providing the link between the heart and liver showing how liver-diseases predispose to impairment in heart functioning and vice versa. Considering the growing number of patients living (and living longer) with heart failure and/or congenital heart disease, it is important to know when and how to test for liver disease in this population, how to interpret abnormal test results, and what management is appropriate. Coverage includes what should be done for patients to limit, avoid, or postpone the impairment in the liver functioning induced by heart diseases and the impairment in the heart functioning induced by liver diseases, on the basis of scientific-exposed evidence and patho-physiology knowledge.
Cardio Hepatology Connections Between Hepatic and Cardiovascular Disease 1st Table of contents:
Part I: Liver and heart
Chapter 1. The liver–heart relationship: a history
Abstract
Introduction
The ancient world: east and west
The medieval era
The modern era
References
Chapter 2. Nonalcoholic fatty liver disease and cardiovascular disease
Abstract
Introduction
The definition of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Association between nonalcoholic fatty liver disease/nonalcoholic steatohepatitis and cardiovascular disease
Dyslipidemia as causative factors for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis and cardiovascular disease
Possible underlining molecular mechanisms between nonalcoholic steatohepatitis and atherosclerosis
Association between NAFLD/hepatic fibrosis and cardiac dysfunction
Conclusion
References
Chapter 3. Pathophysiologic changes in chronic heart failure affecting drug pharmacokinetics
Abstract
Introduction
Fundamental clinical pharmacokinetic principles
Pathophysiological changes affecting pharmacokinetics in patients with chronic heart failure
Pharmacotherapeutic implications: general recommendations
Conclusion
References
Chapter 4. Drugs at the crossroads of heart and liver
Abstract
Introduction
Part 1: amiodarone
Part 2: beta-blockers
The concept of a therapeutic window of nonselective beta-blockers in decompensated cirrhosis
Summary and current recommendations
References
Chapter 5. Obstruction of the liver circulation
Abstract
Introduction
Budd–Chiari syndrome
Risk factors
Natural history
Staging and prognosis
Treatment and management of complications
Noncirrhotic nontumoral portal vein thrombosis
Risk factors
Diagnosis and staging
Natural history
Treatment of recent nontumoral portal vein thrombosis
Treatment of chronic nontumoral portal vein thrombosis
Sinusoidal obstruction syndrome
Diagnosis
Preventive measures
Treatment
Hepatic artery thrombosis
Etiology and risk factors
Clinical presentation
Treatment
Acknowledgment
Conflict of interest statement
Financial support
References
Part II: Hepatobiliary system in heart failure
Chapter 6. Epidemiology of liver diseases in heart failure
Abstract
Introduction
The liver diseases in patients with heart failure
Diseases leading to heart failure and affecting the liver
References
Chapter 7. Cardio-hepatology: liver function tests in heart failure
Abstract
Liver function tests
Blood supply of the liver and its anatomy
Pathophysiology of abnormal liver function tests in heart failure
Bilirubin metabolism in the liver
Association between abnormal liver function tests and impaired hemodynamics
Liver function tests and prognosis in heart failure
References
Chapter 8. Prognostic value of liver assessment (including liver stiffness measurement) in cardiovascular diseases
Abstract
Introduction
Heart failure and liver impairment
Liver disease is associated with poor outcome of heart failure
Liver disease is associated with poor outcomes of cardiovascular diseases
Liver function tests and prognosis of HF
Markers of hepatic fibrosis and prognosis of HF
Imaging markers of hepatic fibrosis in HF
Summary
References
Chapter 9. Passive liver congestion and hypoxic hepatitis
Abstract
Introduction
Passive liver congestion
Conclusion
References
Chapter 10. Histopathology of the liver in heart failure
Abstract
Introduction
Natural history
Pathological analysis
Pathogenesis
Conclusion
References
Chapter 11. The Fontan procedure and liver disease
Abstract
Introduction
Fontan procedure
Physiology and prevalence of Fontan-associated liver disease
Examination to detect Fontan-associated liver disease
Recommendation
References
Part III: Cardiovascular system in liver failure
Chapter 12. Sepsis and the liver
Abstract
Introduction
Sepsis in the general population
Sepsis in patients with cirrhosis
Conclusions
Acknowledgments
References
Chapter 13. Bleeding and thrombosis in cirrhosis
Abstract
Introduction to hemostasis
Hemostatic changes in liver diseases
Pitfalls of routine diagnostic tests of hemostasis
The concept of rebalanced hemostasis
Hemostatic balance in different types and severities of liver diseases
Bleeding in liver diseases
Thrombosis in liver diseases
Intrahepatic thrombosis and disease progression
Hemostasis and liver regeneration
Conclusion
References
Chapter 14. Peripheral vasculature in portal hypertension
Abstract
Introduction
Hyperdynamic circulation
Increased blood and plasma volume/decreased effective circulating volume
Peripheral venous “sump” effect due to venous pooling
Abnormalities of arterial vascular tone
Nervous system and peripheral vascular changes
Management of hyperdynamic circulation
Conclusions
References
Chapter 15. Cirrhotic cardiomyopathy
Abstract
Introduction
Definition and diagnostic criteria
Clinical significance
Morbidity/mortality after cardiovascular challenges
Cirrhotic cardiomyopathy and prognosis
Pathogenic mechanisms
TNFα
β-Adrenergic signaling
Membrane fluidity
Bile acids
Nitric oxide
Carbon monoxide
Myosin heavy chain isoform shift
The role of ion channels in cirrhotic cardiomyopathy
Titin and collagen isoforms
Endocannabinoids
Management
Liver transplantation
Conclusion
References
Chapter 16. Cardiovascular dysfunction in liver diseases: pediatric perspectives
Abstract
Introduction
Cardiovascular consequences of structural congenital heart diseases coexisting with diseases of the liver
Cardiovascular complications of pediatric cirrhosis
Mechanistic insights into bile acid-myocardial interaction
Cardiovascular consequences of inherited metabolic liver failure and failure of energy metabolism
Cardiovascular consequences of acute liver failure
Cardiovascular consequences of chronic cirrhosis, portal hypertension, and portosystemic shunts
Cardiovascular consequences of immunotherapy used in liver transplants
Evaluation of the cardiovascular status before liver transplantation
Future directions and opportunities for research
References
Chapter 17. Hepatorenal syndrome and acute kidney injury in cirrhosis
Abstract
Introduction
The evolving concept of renal dysfunction in cirrhosis
Definition and diagnostic criteria of acute kidney injury in cirrhosis
Epidemiology
Pathophysiology
Hemodynamic changes in cirrhosis
Cardiac dysfunction in cirrhosis
The role of inflammation
Predictive factors for the development of hepatorenal syndrome-acute kidney injury
Diagnosis
Biomarkers
Management
General measures
Albumin
Vasoconstrictors
Renal replacement therapy
Liver transplantation
Combined liver kidney transplant
Prognosis
Prevention
Conclusion
References
Chapter 18. Cardiopulmonary considerations for the anesthetic management of liver transplantation
Abstract
Perioperative cardiovascular management in the liver transplant patient
Perioperative pulmonary management in the liver transplant recipient
References
Chapter 19. Cardiovascular assessment before liver transplantation
Abstract
Introduction
References
Chapter 20. Predicting cardiovascular complications after liver transplantation
Abstract
Introduction
Epidemiology and established risk factors for cardiovascular complications in liver transplantation
Natural history and timing of cardiovascular events in liver transplantation
Algorithms and risk calculators for prediction of cardiovascular risk after liver transplantation
Conclusions
References
Index
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