Clinical Gynecologic Oncology 9th Edition by Philip J. Disaia, William T. Creasman, Robert S Mannel, Scott McMeekin, David G Mutch – Ebook PDF Instant Download/DeliveryISBN: 0323443176, 9780323443173
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Product details:
ISBN-10 : 0323443176
ISBN-13 : 9780323443173
Author : Philip J. Disaia, William T. Creasman, Robert S Mannel, Scott McMeekin, David G Mutch
The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A “who’s who” list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference.
Clinical Gynecologic Oncology 9th Table of contents:
1 Preinvasive Disease of the Cervix
Natural History
Epidemiology
Human Papillomavirus Vaccination
Screening
Core Principles for Managing Abnormal Screening Test Results
Managing Abnormal Cervical Cancer Screening Test Results
Postcolposcopy Management
Treatment of Cervical Disease
Managing Abnormal Results During Pregnancy
Future Directions
Bibliography
2 Preinvasive Disease of the Vagina and Vulva and Related Disorders
Embryology
Examination and Treatment of Females Exposed to Diethylstilbestrol
Nonneoplastic Epithelial Disorders of the Vulva
Intraepithelial Neoplasia of the Vagina
Vulvar Intraepithelial Neoplasia
Bibliography
3 Invasive Cervical Cancer
General Observations
Microinvasive Carcinoma of the Cervix
Clinical Profile of Invasive Cancer
Glandular Tumors of the Cervix
Staging
Treatment of Early-Stage Disease
Treatment of Locally Advanced Disease
Neuroendocrine and Other Uncommon Tumors of the Cervix
Glassy Cell Carcinoma, Carcinosarcoma, Lymphoma, and Melanoma
Survival Results and Prognostic Factors for Early-Stage and Locally Advanced Disease
Recurrent and Advanced Carcinoma of the Cervix
Bibliography
4 Endometrial Hyperplasia, Estrogen Therapy, and the Prevention of Endometrial Cancer
Introduction
Clinical Presentation
Endometrial Hyperplasia: Pathologic Diagnostic Criteria
Management Decisions for Atypical Endometrial Hyperplasia (Endometrial Intraepithelial Neoplasia)
Management of Endometrial Hyperplasia Without Atypia
Prevention of Endometrial Cancer
Benefits and Risks of Estrogen Replacement Therapy
Estrogen Replacement Therapy for Endometrial and Breast Cancer Survivors
Bibliography
5 Adenocarcinoma of the Uterine Corpus
Incidence
Epidemiology
Diagnosis
Prognostic Factors
Treatment
Bibliography
6 Sarcoma of the Uterus
Classification
Incidence and Epidemiology
Leiomyosarcoma
Endometrial Stromal Sarcoma
Other Sarcomas
Bibliography
7 Gestational Trophoblastic Disease
Hydatidiform Mole
Gestational Trophoblastic Neoplasia
Other Considerations
Bibliography
8 Invasive Cancer of the Vulva
Invasive Squamous Cell Carcinoma
Sentinel nodes
Early Vulvar Carcinoma
Paget Disease
Melanoma
Sarcoma
Bartholin Gland Carcinoma
Basal Cell Carcinoma
Bibliography
9 Invasive Cancer of the Vagina
Squamous Cell Carcinoma of the Vagina
Rare Histologies
Bibliography
10 Adnexal Masses
Adnexal Masses
Extraovarian Adnexal Masses
Ovarian Masses
Management of Adnexal Masses
Special Circumstances
Bibliography
11 Epithelial Ovarian Cancer
Classification
Incidence, Epidemiology, and Etiology
Signs, Symptoms, and Attempts at Early Detection (Screening)
Diagnostic Techniques and Staging
Therapeutic Options for Primary Treatment
Follow-Up Techniques and Treatment of Recurrences
Rehabilitation
Conclusions on Management
Current Areas of Research
Bibliography
12 Germ Cell, Stromal, and Other Ovarian Tumors
Germ Cell Tumors
Tumors of Germ Cell and Sex Cord Derivation
Tumors Derived From Special Gonadal Stroma
Tumors Derived From Nonspecific Mesenchyme
Malignant Lymphoma
Metastatic Tumors to the Ovary
Malignant Ovarian Tumors in Children
Bibliography
13 Fallopian Tube Cancer
Introduction
Traditional Characteristics
Emerging Paradigms
Clinical Implications
Conclusion
Bibliography
14 Breast Diseases
Introduction
Anatomy of the Breast
Embryology and Development of the Breast
Pregnancy and Breastfeeding
Benign Breast Conditions
History and Physical Examination
Mammography
Breast Ultrasonography and Magnetic Resonance Imaging
Diagnostic Evaluation
Epidemiology of Breast Cancer
Risk Factors and Assessment
Pathology
Biologic Markers and Prognostic Factors
Staging of Breast Cancer Using the Tumor–Node–Metastasis System
Treatment of Breast Cancer
Special Issues
Conclusions
Bibliography
15 Cancer in Pregnancy
Background and Epidemiology of Cancer in Pregnancy
The More Common Solid Tumors in Pregnancy
Evaluation and Therapeutic Modalities
Hematologic Malignancies in Pregnancy
Other Tumors in Pregnancy
Bibliography
16 Complications of Disease and Therapy
Disease–Oriented Complications
Treatment-Related Complications
Bibliography
17 Basic Principles of Chemotherapy
Historical Overview
General Principles
Cell Cycle Control and Growth Kinetics
Dynamics of Chemotherapy
Pharmacologic Principles
Categories of Drugs in Current Use (Table 17.7)
Drug Toxicity
Evaluation of New Agents
Bibliography
18 Targeted Therapy and Molecular Genetics
Targeted Therapy
Foundation of Targeted Therapy
Targeted Agents
Angiogenesis
Vascular Endothelial Growth Factors and Vascular Endothelial Growth Factor Receptors
Phosphatidylinositol-3-Kinase/AKT Pathway
Ras/Raf Pathway
Poly-ADP-Ribose Polymerase Pathway
Epidermal Growth Factor Receptor Pathway
Multipathway Targeted Agents
Other Targets of Interest
Unique Toxicities of Targeted Therapy
Special Considerations for Targeted Therapies
Conclusions
Acknowledgments
Bibliography
19 Genes and Cancer
Genetic Alterations in Cancer
Mechanisms of Human Gene Mutation
Cancer Epigenetics
Genomic Imprinting and Cancer
Genetic Alterations That Cause Cancer
Hereditary Cancer Risk Assessment: Genetic Counseling and Genetic Testing
Genetic Counseling and Genetic Testing for Hereditary Cancers
Referral of Gynecologic Cancer Patients for Hereditary Cancer Risk Assessment
Genetic Testing
Legal Aspects of Genetic Testing
Long-Term Contact for Patients and Families With Hereditary Risk for Cancer
DNA Banking
Conclusion
Glossary
Bibliography
20 Palliative Care and Quality of Life
Evolution of Palliative Care
Quality of Life in Gynecologic Cancers
Management of Common Physical Symptoms
Psychosocial and Spiritual Needs of Patients and Families
Management of Psychosocial and Spiritual Distress
Quality of Life Issues in Advanced and Recurrent Ovarian Cancer
Quality of Life Issues in Advanced and Recurrent Uterine and Cervical Cancer
End-of-Life Decision Making
Bibliography
21 Role of Minimally Invasive Surgery in Gynecologic Malignancies
Laparoscopic Surgery in Gynecologic Oncology
Laparoscopic Surgical Staging of Gynecologic Malignancies
Robotic Surgery in Gynecologic Malignancies
Minimally Invasive Surgery Learning Curve
Minimally Invasive Surgical Technique
Applications of Minimally Invasive Surgery in Gynecologic Oncology
Complications of Laparoscopic Surgery
Conclusions
Bibliography
22 Epidemiology of Commonly Used Statistical Terms and Analysis of Clinical Studies
Epidemiology
Evidence-Based Medicine
Measures in Epidemiology
Analysis of Clinical Trials
Types of Clinical Trials
Evaluation of Clinical Trials
Bibliography
23 Basic Principles in Gynecologic Radiotherapy
Introduction to Electromagnetic Radiation
Radiation Units
Radiation Physics
Radiobiology
Radiosensitizers, Hypoxic Cell Sensitizers, and Radioprotectors
Principles of Clinical Radiation Therapy
New Radiation Modalities
New Radiation Delivery Technology
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