Copper in N-Heterocyclic Chemistry 1st Edition by Ananya Srivastava – Ebook PDF Instant Download/DeliveryISBN: 012821547X, 9780128215470
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ISBN-10 : 012821547X
ISBN-13 : 9780128215470
Author: Ananya Srivastava
Copper in N-Heterocyclic Chemistry provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, covering all recent developments in a way that is ideal for researchers and students working in the area of synthetic organic chemistry and medicinal chemistry. The book explores N-heterocyclic compounds as unique structural units in the development of natural products and pharmaceuticals, along with the remarkable progress made in the area of high atom economic strategies, and more recently, copper-catalyzed C-H activation and its applications in organic synthesis. Readers will find troubleshooting protocols, as well as the advantages and limitations of each method discussed.
Copper in N-Heterocyclic Chemistry 1st Table of contents:
Chapter 1: Copper-catalyzed synthesis of aziridines
Abstract
Acknowledgments
1: Introduction
2: Asymmetric nucleophilic addition to 2H-azirines
3: Reaction of aziridines and oxaziridines
4: Cycloaddition reactions
5: Cyclization reaction/Baldwin rearrangement
6: Copper-catalyzed C–H amination reaction
7: Aziridination via intramolecular SN2 substitution
8: Aziridination of imines via carbene transfer
9: Aziridination of olefins via nitrene transfer
Chapter 2: Copper catalysis for imidazoles and pyrazoles
Abstract
1: Introduction
2: Synthesis of imidazole and its congener using copper catalyst
3: Synthesis of benzimidazole and its congener by using copper catalyst
4: Synthesis of pyrazole and its congener by using copper catalyst
5: Conclusion
Chapter 3: Copper catalysis in the synthesis of 1,2,3-triazoles and tetrazoles
Abstract
1: Introduction
2: Properties of 1,2,3-triazoles and tetrazoles
3: Synthetic strategies for the synthesis of 1,2,3-triazole and tetrazole nucleus
4: Recent developments in copper catalysis in the synthesis of 1,2,3-triazoles and tetrazoles
Chapter 4: Copper catalysis for pyridines and pyrimidines
Abstract
1: Introduction
2: Conclusion
Chapter 5: Copper catalysis for triazines
Abstract
Acknowledgment
1: Introduction
2: Synthesis
3: Modification of triazines
4: Conclusion
Chapter 6: Copper catalysis for pyrazines and quinoxalines
Abstract
Acknowledgment
1: Introduction
2: Synthesis of quinoxaline and its congener using copper catalyst
3: Synthesis of pyrazine and its congener using copper catalyst
4: Conclusion
Chapter 7: Copper catalysis for the synthesis of quinolines and isoquinolines
Abstract
1: Introduction
2: Copper-catalyzed synthesis of quinolines
3: Copper-catalyzed synthesis of isoquinolines
4: Summary
Chapter 8: Copper-mediated synthesis of quinazolines and related benzodiazines
Abstract
1: Introduction
2: Synthesis of quinazoline derivatives by Cu-mediated condensation/oxidation
3: Synthesis of quinazoline derivatives via Ullmann-Goldberg reaction
4: Synthesis of quinazoline derivatives using miscellaneous methods
5: Synthesis of polycyclic quinazoline derivatives
6: Cu-mediated synthesis of other benzodiazines
7: Modification of quinazoline and quinoxaline scaffolds
8: Conclusion
Chapter 9: Copper catalysis for large rings
Abstract
1: Introduction
2: Copper-catalyzed “click” reaction for the construction of aza-macrocycles
3: Copper-catalyzed N-arylation for the construction of aza-large ring
4: Copper-catalyzed atom transfer radical cyclization reactions
5: Conclusions and outlook
Chapter 10: Copper catalysis for saturated N-heterocycles via C–H functionalization
Abstract
1: Introduction
2: Four-membered saturated N-heterocycles
3: Five-membered saturated N-heterocycles
4: Six-membered saturated N-heterocycles
5: Seven-membered saturated N-heterocycles
6: Summary
Chapter 11: Pursuit for simple and efficient ligands promoting copper-catalyzed Ullmann type reactions for N-aryl heterocycles and aromatic amines
Abstract
Acknowledgments
1: Introduction
2: Ligands in Ullmann reaction: Mechanism for CN bond formation
3: Ligands in CN bond formation
4: Ligands for promoting Cu-catalyzed CN bond formation in material and drug development
5: Conclusions
Chapter 12: Solid supported copper for N-heterocycles
Abstract
Acknowledgments
1: Supported nanocatalysts
2: Catalysis by Cu-MOFs
3: Supported copper salts and complexes
Chapter 13: Copper catalysis for biologically active N-heterocycles*
Abstract
1: Introduction
2: Synthesis of N-heterocycles and their biological activities
3: Conclusion
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Copper,Heterocyclic,Chemistry,Ananya Srivastava