(EBook PDF) Critical thinking in clinical research applied theory and practice using case studies 1st edition by Felipe Fregni, Ben Illigens 0199324514 9780199324514 full chapters

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ISBN-10 :  0199324514 

ISBN-13 :  9780199324514

Author : Felipe Fregni, Ben M.W. Illigens 

One of the most crucial skills a clinician, scientist, or student can learn is to create, conduct, and interpret the conclusions of a clinical study. Critical Thinking in Clinical Research teaches these fundamentals in four distinct sections, called “units”: the first unit focuses on issues surrounding the design of a study such as population, question selection, randomization, and blinding; Unit 2 presents statistical methods such as analyzing data collected, how to present and discuss the data concisely; the third unit covers practical aspects such as methodology, organizational considerations, principles of trial conduct and reporting; and the final unit delves into study designs, providing the advantages and drawbacks of each design style. Each chapter begins with a short introduction, followed by a hypothetical case that challenges the reader to make decisions, to consider pros and cons of specific approaches, and to evaluate options based on specific conditions. Knowing how to critically read and understand scientific papers and to collect, analyze, and interpret research data, which they in turn can then present in their own scientific manuscript makes this book the perfect resource for anyone looking to contribute to the wealth of scientific and medical inquiry.

Critical thinking in clinical research : applied theory and practice using case studies 1st Table of contents:

Unit I: Basics of Clinical Research
1. Basics of Clinical Research: Introduction to Clinical Research
2. Selection of the Research Question
3. Study Population
4. Basic Study Designs
5. Randomization
6. Blinding
7. Recruitment and Adherence
Unit II: Basics of Statistics
8. Basics of Statistics
9. Parametric Statistical Tests
10. Non-Parametric Statistical Tests
11. Sample Size Calculation
12. Survival Analysis
13. Other Issues in Statistics I: Missing Data, Intention-to-Treat Analysis, and Covariate Adjustment
14. Other Issues in Statistics II: Subgroup Analysis and Meta-analysis
Unit III: Practical Aspects of Clinical Research
15. Non-Inferiority Design
16. Observational Studies
17. Confounders and Using the Method of Propensity Scores
18. Adaptive Trials and Interim Analysis
Unit IV: Study Designs
19. Integrity in Research: Authorship and Ethics
20. The Business of Clinical Research
21. Design and Analysis of Surveys
22. Assessing Risk and Adverse Events
23. Manuscript Submission

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