Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems: Volume 2: Expectations and Realities of Multifunctional Drug Delivery Systems 1st Edition by Ranjita Shegokar – Ebook PDF Instant Download/DeliveryISBN: 0128177778, 9780128177778
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Product details:
ISBN-10 : 0128177778
ISBN-13 : 9780128177778
Author : Ranjita Shegokar
Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems, Volume Two examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects.
This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders. This level of discussion makes it a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about the status of drug delivery systems.
Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems: Volume 2: Expectations and Realities of Multifunctional Drug Delivery Systems 1st Table of contents:
Chapter 1. Polymer lipid hybrid (PLH) formulations: a synergistic approach to oral delivery of challenging therapeutics
1. Introduction
2. Structure and composition of polymer–lipid hybrid (PLH) systems
3. Conclusions
Chapter 2. Dendrimers for pharmaceutical applications—potential and challenges
1. Introduction
2. Dendrimers in general
3. Dendrimers as drugs and delivery system
4. Toxicity
5. Synthesis and engineering aspects
6. Purification
7. Issues related to up-scaling
8. Conclusions and outlook
Chapter 3. Electrospun nanofibers for biomedical applications
1. Introduction
Chapter 4. Nanocarriers for topical delivery in psoriasis
1. Introduction
2. Skin
3. Psoriasis
4. Conventional treatments
5. Need for nanocarriers
6. Nanocarriers as drug-delivery systems in psoriasis
7. RNA-directed treatment in psoriasis
8. Conclusion and future perspectives
Chapter 5. Mitochondria-targeted drug delivery in neurodegenerative diseases
1. Introduction
2. Mitochondrial dysfunction and neurodegenerative diseases
3. Mitochondria: as a target for drug delivery in neurodegenerative disease
4. Mitochondrial targeting in neurodegenerative diseases and the blood–brain barrier
5. Nanoparticles for mitochondrial targeting
6. Nano drug delivery: clinical challenges
7. “Nano” drug delivery: regulations
8. Conclusion
Abbreviations
Chapter 6. Nano-structured microparticles for inhalation
1. The lung as a route of administration
2. Common approach for the preparation of nano-embedded microparticles
3. Methods for the production of nonspherical particles
4. Conclusion
Chapter 7. Physical approaches for drug delivery: an overview
1. Introduction
2. Overview of viral and chemical methods for drug delivery
3. Physical methods for drug delivery
4. Challenges and future prospects
5. Conclusions
Chapter 8. Complex injectables: development, delivery, and advancement
1. Introduction
2. Peptide-based complex injectables
3. Characterization techniques for proteins and peptides
4. Injectors
5. Conclusion
Chapter 9. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in colorectal cancer treatment
1. Introduction
2. Intraperitoneal chemotherapy beginnings
3. Anatomopathology
4. Cytology
5. Quality of life and the Karnofsky index (KI)
6. Drug-delivery evaluation
7. Cytoreductive characteristics
8. Conclusions
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