Fundamentals of Drug Delivery 1st Edition Heather A. E. Benson

Fundamentals of Drug Delivery 1st Edition Heather A. E. Benson – Ebook Instant Download/Delivery ISBN(s): 9781119769606,9781119769651,9781119769675,1119769604,1119769655,1119769671,2021033395,2021033396

Product details:

• ISBN-10 ‏ : ‎ 1119769604
• ISBN-13 ‏ : ‎ 978-1119769606
• Author: Heather A. E. Benson 

Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery.

Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics.

Table of contents:

Part I Product Design, the Essence of Effective Therapeutics

1 Challenges and Innovations of Controlled Drug Delivery

2 Challenges in Design of Drug Delivery Systems

3 Drug Delivery of the Future

4 The Pharmaceutical Drug Development Process: Selecting a Suitable Drug Candidate

5 Preformulation and Physicochemical Characterization Underpinning the Development of Controlled Drug Delivery Systems

6 Mathematical Models Describing Kinetics Associated with Controlled Drug Delivery Across Membranes

7 Understanding Drug Delivery Outcomes: Progress in Microscopic Modeling of Skin Barrier Property, Permeation Pathway,

8 Role of Membrane Transporters in Drug Disposition 193
Hong Yang and Yan Shu

Part II Challenges in Controlled Drug Delivery and Advanced Delivery Technologies 231

9 Advanced Drug Delivery Systems for Biologics 233
May Wenche Joraholmen, Selenia Ternullo, Ann Mari Holsaeter, Goril Eide Flaten, and Nataša Škalko-Basnet

10 Recent Advances in Cell-Mediated Drug Delivery Systems for Nanomedicine and Imaging 263
Li Li and Zhi Qi

11 Overcoming the Translational Gap – Nanotechnology in Dermal Drug Delivery 285
Christian Zoschke and Monika Schafer-Korting

12 Theranostic Nanoparticles for Imaging and Targeted Drug Delivery to the Liver 311
Haolu Wang, Haotian Yang, Qi Ruan, Michael S. Roberts, and Xiaowen Liang

13 Toxicology and Safety of Nanoparticles in Drug Delivery System 329
Klintean Wunnapuk

Part III Administrative Routes for Controlled Drug Delivery 349

14 Controlled Drug Delivery via the Ocular Route 351
Peter W.J. Morrison and Vitaliy V. Khutoryanskiy

15 Controlled Drug Delivery via the Otic Route 377
Jinsong Hao and S. Kevin Li

16 Controlled Drug Delivery via the Nasal Route 393
Barbara R. Conway and Muhammad U. Ghori17 Controlled Drug Delivery via the Buccal and Sublingual Routes 433
Javier O. Morales, Para

meswara R. Vuddanda, and Sitaram Velaga

18 Controlled Drug Delivery via the Lung 449
Maria V. Ramirez-Rigo, Nazareth E. Ceschan, and Hugh D. C. Smyth

19 Controlled Drug Delivery via the Vaginal and Rectal Routes 471
Jose das Neves and Bruno Sarmento

20 Controlled Drug Delivery into and Through Skin 507

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