Genes Environment and Alzheimers Disease 1st Edition by Orly Lazarov, Giuseppina Tesco 0128028513 978-0128028513

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ISBN-10 ‏ : ‎ 0128028513

ISBN-13 ‏ : ‎ 978-0128028513

Author : Orly Lazarov, Giuseppina Tesco

Genes, Environment and Alzheimer’s Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline.

It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.

 

Genes, Environment and Alzheimer’s Disease 1st Table of contents:

Chapter 1 – Molecular Mechanisms of Learning and Memory

Chapter 2 – When Cognitive Decline Becomes Pathology: From Normal Aging to Alzheimer’s Disease

Chapter 3 – Adult Neurogenesis and Cognitive Function: Relevance for Disorders Associated with Human Aging

Chapter 4 – The Amyloid β Precursor Protein and Cognitive Function in Alzheimer’s Disease

Chapter 5 – Molecular Pathways in Alzheimer’s Disease and Cognitive Function: New Insights into Pathobiology of Tau

Chapter 6 – Apolipoprotein E and Amyloid-β-Independent Mechanisms in Alzheimer’s Disease

Chapter 7 – Lifestyle and Alzheimer’s Disease: The Role of Environmental Factors in Disease Development

Chapter 8 – Role of BACE1 in Cognitive Function, from Alzheimer’s Disease to Traumatic Brain Injury

Chapter 9 – Traumatic Brain Injury and Rationale for a Neuropsychological Diagnosis of Diffuse Axonal Injury

Chapter 10 – Alzheimer’s Disease and the Sleep–Wake Cycle

Chapter 11 – Stroke, Cognitive Function, and Alzheimer’s Disease

Chapter 12 – Cerebral Innate Immunity: A New Conceptual Framework for Alzheimer’s Disease

Chapter 13 – Type 2 Diabetes Mellitus as a Risk Factor for Alzheimer’s Disease

 

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Tags: Genes, Environment, Alzheimers Disease, Orly Lazarov, Giuseppina Tesco