Genetic Analysis of Complex Disease – Ebook Instant Download/Delivery ISBN(s): 9781118123911,9781119104100,9781119104087,9781119104070,1118123913,1119104106,1119104084,1119104076
Product details:
- ISBN-10 : 1118123913
- ISBN-13 : 978-1118123911
- Author:
In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies.
This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues.
Table contents:
1 Designing a Study for Identifying Genes in Complex Traits
2 Basic Concepts in Genetics
3 Determining the Genetic Component of a Disease
4 Study Design for Genetic Studies
5 Responsible Conduct of Research in Genetic Studies
6 Linkage Analysis
7 Data Management
8 Linkage Disequilibrium and Association Analysis
10 Bioinformatics of Human Genetic Disease Studies
11 Complex Genetic Interactions/Data Mining/Dimensionality Reduction
12 Sample Size, Power, and Data Simulation
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