Handbook of the Biology of Aging 9th Edition

Handbook of the Biology of Aging 9th Edition – Ebook Instant Download/Delivery ISBN(s): 9780128159620,0128159626,9780128162835, 012816283X

Product details:

• ISBN-10: 012816283X
• ISBN-13: 9780128162835
• Author: Nicolas Musi

Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, and much more.

Table contents:

Chapter 1. Longevity as a complex genetic trait

Chapter 2. DNA damage and repair in aging

Chapter 3. Mechanisms of cell senescence in aging

Chapter 4. The nature of aging and the geroscience hypothesis

Chapter 5. Sirtuins, healthspan, and longevity in mammals

Chapter 6. Integrative genomics of aging

Chapter 7. Thermogenesis and aging

Chapter 8. Yeast as a model organism for aging research

Chapter 9. Model organisms (invertebrates)

Chapter 10. NIA Interventions Testing Program: A collaborative approach for investigating interventions to promote healthy aging

Chapter 11. Aging in nonhuman primates

Chapter 12. Senotherapeutics: Experimental therapy of cellular senescence

Chapter 13. The role of neurosensory systems in the modulation of aging

Chapter 14. Aging of the sensory systems: hearing and vision disorders

Chapter 15. Cardiac aging

Chapter 16. The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention

Chapter 17. Microbiome changes in aging

Chapter 18. Lipidomics of aging

Chapter 19. Trends in morbidity, healthy life expectancy, and the compression of morbidity

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