Hyphenations of Capillary Chromatography with Mass Spectrometry 1st Edition by Peter Tranchida 012809639X 9780128096390

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ISBN-10 :  012809639X 

ISBN-13 :  9780128096390 

Author :  Peter Q. Tranchida 

Hyphenations of Capillary Chromatography with Mass Spectrometry provides comprehensive coverage of capillary chromatography with mass spectrometry—both single and multidimensional approaches. The book examines nearly all capillary chromatography approaches, combined with a variety of MS forms, giving readers a wide and detailed view on current-day analytical strategies and applications. Of particular focus are novel developments in the field of MS, such as the Orbitrap, HR ToF, ToF MS with variable electron-impact energy, fast MS-MS and APGC technology.

Junior scientists conducting research on mono-dimensional chromatography-MS fundamental relationships and experienced analytical chemists working in conventional capillary chromatography and classical multidimensional chromatography will find this an ideal application-based reference on the hyphenations of these domains.

Hyphenations of Capillary Chromatography with Mass Spectrometry 1st Table of contents:

Part 1. Hyphenation of capillary gas chromatography with mass spectrometry
Chapter 1.1. General principles and history
1.1.1. Introduction
1.1.2. GC fundamentals in the perspective of hyphenation and speed of analysis
1.1.3. Instrumental factors of MS
1.1.4. Recent developments in sample preparation for GC-MS
1.1.5. Applications, miniaturization, and future of hyphenated GC-MS
Chapter 1.2. Conventional GC-MS applications
1.2.1. Introduction
1.2.2. Low-resolution MS applications
1.2.3. High-resolution MS applications
1.2.4. Multiple MS analyzer experiments
Chapter 1.3. High-speed GC-MS: Basic theory, practical aspects, and applications
1.3.1. Introduction
1.3.2. High-speed GC-MS methodologies: basic theory, practical aspects and applications
Part 2. Two-dimensional capillary gas chromatography-based processes combined with mass spectrometry
Chapter 2.1. Classical two-dimensional GC combined with mass spectrometry
2.1.1. History, general principles, and theoretical aspects
2.1.2. Instrumentation and configurations
2.1.3. State-of-the-art applications
2.1.4. Conclusions and outlook
Chapter 2.2. Comprehensive 2D Gas Chromatography
2.2.1. History, general principles, practical issues, and basic theoretical aspects
2.2.2. State-of-the-art applications
2.2.3. Conclusions and future prospects
Chapter 2.3. Classical and comprehensive 2D LC-GC
2.3.1. Introduction
Part 3. Hyphenation of oneand two-dimensional capillary liquid chromatography with mass spectrometry
Chapter 3.1. History of liquid chromatography—mass spectrometry couplings
3.1.1. Introduction
3.1.2. Low-pressure ionization
3.1.3. Atmospheric-pressure ionization
3.1.4. Summary and outlook
Chapter 3.2. Theoretical and practical aspects of LC-MS analysis
3.2.1. Introduction
3.2.2. Vacuum systems
3.2.3. Mass analyzers
3.2.4. Concluding remarks
Chapter 3.3. Hyphenations of one-dimensional capillary liquid chromatography with mass spectrometry: State-of-the-art applications
3.3.1. Introduction
3.3.2. Macro-biomolecules and capillary LC-MS
3.3.3. Small biomolecules and capillary LC
3.3.4. Capillary LC-MS: drugs, environment, and foods
3.3.5. Capillary LC coupled with alternatives of ESI-MS
3.3.6. Conclusions
Chapter 3.4. Hyphenations of 2D capillary-based LC with mass spectrometry
3.4.1. Introduction
3.4.2. History, general principles, and theoretical aspects
3.4.3. Instrumental setup and practical aspects
3.4.4. State-of-art applications
3.4.5. Conclusions and future perspectives
Chapter 4. Capillary electrophoresis-mass spectrometry: History, general principles, theoretical aspects, and state-of-the-art applications
4.1. Introduction
4.2. Brief history, theory, and general principles
4.3. Hyphenation with mass spectrometry
4.4. Two-dimensional separation methods
4.5. Selected examples of CE-MS applications
4.6. Conclusions and perspectives
Chapter 5. Management and interpretation of capillary chromatography-mass spectrometry data
5.1. Introduction and scope
5.2. Data management and analysis of variance
5.3. Preprocessing
5.4. Deconvolution
5.5. Classification and comparison
5.6. Targeted analysis
5.7. Non-targeted analysis
5.8. Hybrid targeted/non-targeted analysis
5.9. Conclusion

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Tags: Hyphenations, Capillary, Chromatography, Mass Spectrometry, Peter Tranchida