Mayo Clinic Cases in Neuroimmunology (Mayo Clinic Scientific Press) Andrew 0197583431 9780197583432

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Product details:

• ISBN-10: 0197583431 
• ISBN-13: 9780197583432
• Author: Andrew Mckeon

Mayo Clinic Cases in Neuroimmunology delivers a case-based walk-through of demyelinating, autoimmune, and other inflammatory neurologic disorders and their mimics. The authors present cases from their own extensive experience with common and rare neuroimmunologic disorders. The format of this case-based book was developed to stimulate consideration of the differential diagnosis as the reader reviews the history and examination narratives of each of the 83 cases. Videos of autoimmune movement disorders supplement the clinical descriptions, where pertinent. In addition, test results from radiology, electrophysiology, and laboratory studies are presented, and treatment and outcome data are also included. Clinical pearls and radiologic clues to assist informed diagnostic decision-making are emphasized. Each case is followed by discussion, including therapeutic guidance and key take-home points. More than 150 multiple-choice questions with answers are also given to test readers’ comprehension and retention. This new addition to the Mayo Clinic Scientific Press series is a comprehensive volume on neuroimmunology that will stimulate and inform those aiming for clinical mastery.

Table of contents:

Section I CNS Demyelinating Disease
Case 1 A Woman With Subacute Painful Vision Loss
Case 2 Rapidly Progressive Numbness and Weakness After Soft-​Tissue Abscess
Case 3 Weakness With Neck Flexion
Case 4 New-​Onset Right-​Sided Numbness and Double Vision
Case 5 Progressive Left Lower Extremity Weakness and Thoracic Spinal Cord Lesion
Case 6 Progressive Spasticity With a Single Magnetic Resonance Imaging Lesion
Case 7 Fluctuating Vision Loss, Seizures, and Left Parieto-​Occipital Mass
Case 8 Diffuse Pain and Abnormal Brain MRI Findings
Case 9 Lesions Found by Chance
Case 10 Encephalopathy and Quadriparesis After an Upper Respiratory Tract Infection
Case 11 Severe Monocular Vision Loss Followed by Gait Difficulty
Case 12 Multiple Sclerosis and Cognitive Impairment
Case 13 New-​Onset Gait Difficulty With Kappa Free Light Chains in Cerebrospinal Fluid
Case 14 A Girl With Back Pain, Paresthesias, and Painful Vision Loss
Case 15 A Septuagenarian With Progressive Hemiparesis
Case 16 Recurrent Demyelinating Episodes
Case 17 Breakthrough Disease While on Multiple Sclerosis Immunomodulatory Therapy
Case 18 Highly Active Multiple Sclerosis
Case 19 Progressive Gait Difficulties
Case 20 Progressive Cerebellar Ataxia After Natalizumab Treatment
Case 21 Weakness and Dysarthria After Radiosurgery
Section II Autoimmune Neurologic Disorders
Case 22 Fatigue, Blurry Vision, and Swollen Optic Nerves
Case 23 Progressive, Symmetrical, Painless Visual Loss
Case 24 Personality Changes, Cognitive Decline, and Jerking Movements
Case 25 Rapidly Progressive Memory Loss, Mood Change, Mutism, and Abnormal Movements
Case 26 Behavioral and Cognitive Changes Followed by Coma
Case 27 Episodic Hemiparesis, Cognitive Decline, and Seizures in a Woman With Pernicious Anemia
Case 28 Rapidly Progressive Dementia and Thyroid Antibodies
Case 29 Goose Bumps and Memory Loss
Case 30 A Patient With Headache and Progressive Tremor
Case 31 A Man With Flulike Symptoms and Hemorrhagic Brain Lesions
Case 32 Hearing Loss, Imbalance, and Diplopia in a 44-​Year-​Old Man
Case 33 Chorea, Ataxia, and Disturbed Sleep
Case 34 Rapidly Progressive Gait and Coordination Difficulties
Case 35 Dancelike Movements in a Patient With a History of Rash
Case 36 Body Spasms in a Woman With Thyroid Disease
Case 37 Stiffness, Spasms, and Frequent Falls in a 41-​Year-​Old Man
Case 38 Rapid-​Onset Weakness and Numbness in a Patient With Systemic Lupus Erythematosus
Case 39 Progressive Quadriparesis and Cancer
Case 40 Progressive Numbness, Burning Pain, Imbalance, and Dryness
Case 41 Ascending Painful Paresthesias, Progressive Ataxia, and Bilateral Foot Drop
Case 42 Painless, Symmetric, Ascending Weakness and Sensory Loss
Case 43 Difficult-​to-​Treat Polyradiculoneuropathy
Case 44 Autoimmune Peripheral Nervous System Hyperexcitability
Case 45 Orthostatism, Constipation, and Early Satiety
Case 46 Constipation and Syncope
Case 47 Bulbar-​Predominant Weakness
Case 48 Difficulty Climbing the Stairs
Case 49 Rapidly Progressive Proximal Weakness
Case 50 Progressive Weakness and Rash
Case 51 “Restlessness” After Cancer Diagnosis and Treatment
Case 52 Sudden Onset of Diplopia and a Skeletal Muscle Antibody
Section III Other Inflammatory CNS Disorders and Neuroimmunologic Mimics
Case 53 Diplopia, Orbital Pain, and Vision Loss in a Middle-​Aged Woman
Case 54 A Young Man With Visual Field Loss, Decreased Hearing, and Confusion
Case 55 A Woman With Progressive Gait Difficulty and White Matter Abnormalities
Case 56 Progressive Asymmetrical Limb Impairment and Cognitive Decline With Leukoencephalopathy
Case 57 A Woman With Fever, Confusion, and Seizures
Case 58 Encephalopathy With Alternating Hemispheric MRI Abnormalities
Case 59 Rapid-​Onset Hemibody Sensory Loss, Incoordination, and Muscle Jerking
Case 60 A History of Sarcoidosis and a New Brain Lesion
Case 61 Headache and Hemiparesis in Middle Age
Case 62 Subacute Cognitive Decline in an 86-​Year-​Old Woman With Prior Lobar Intracerebral Hem
Case 63 A 75-​Year-​Old Man With 5 Days of Progressive Gait Difficulties and Confusion
Case 64 Night Sweats and Paraparesis
Case 65 A Woman With Headaches and a Tumefactive Brain Lesion
Case 66 Behavioral Change, Seizures, and Temporal Lobe Lesion
Case 67 A Young Woman With Vessel Dissection and Brainstem Lesions
Case 68 Headache, Uveitis, and Leptomeningeal Enhancement
Case 69 Weakness and Punctate Enhancement
Case 70 Bilateral Paresthesias in Crohn Disease
Case 71 Seizures and Enhancing Brain Lesions
Case 72 A Man With Recurrent Headache and Focal Neurologic Deficits
Case 73 Headache, Radicular Pain, and Enhancing Lesions
Case 74 Seizures 3 Months After Endarterectomy
Case 75 Progressive Bilateral Arm Pain, Gait Disturbance, Constipation, and Urinary Retention
Case 76 A Woman With Subacute Numbness of the Trunk, Arms, and Legs
Case 77 A Septuagenarian With Progressive Lower Extremity Weakness and Pain
Case 78 Acute Quadriparesis in a Smoker
Case 79 A 25-​Year-​Old Man With Recurrent Back Pain and Rapid-​Onset Paraplegia
Case 80 Progressive Myelopathy After Neck Pain
Case 81 Progressive Imbalance and Visual Impairment in a Patient With Diabetes
Case 82 Progressive Myelopathy After Spine Surgery
Case 83 Altered Mental Status During the COVID-​19 Pandemic
Section IV Questions and Answers

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