Mechanobiology: From Molecular Sensing to Disease 1st Edition

Mechanobiology: From Molecular Sensing to Disease 1st Edition – Ebook Instant Download/Delivery ISBN(s): 9780128179314,0128179317,9780128179321, 0128179325

Product detail:

• ISBN 10: 0128179325
• ISBN 13: 9780128179321
• Author: Glen L. Niebur

Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology.

• Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli
• Provides a review of diseases with known or purported mechanobiological underpinnings
• Includes the role of mechanobiology in tissue engineering and regenerative medicine
• Covers experimental methods to capture mechanobiological phenomena

Table of contents:

1. Section I. Mechanobiological Basis of Diseases
2. Chapter 1.1. Osteocyte Mechanobiology in Aging and Disease
3. Chapter 1.2. Cardiovascular Mechanics and Disease
4. Chapter 1.3. Mechanobiology of the Optic Nerve Head in Primary Open-Angle Glaucoma
5. Chapter 1.4. The Role of Mechanobiology in Cancer Metastasis
6. Section II. Cellular Basis of Mechanobiology
7. Chapter 2.1. Cells as Functional Load Sensors and Drivers of Adaptation
8. Chapter 2.2. Primary Cilia Mechanobiology
9. Chapter 2.3. In Vivo Models of Muscle Stimulation and Mechanical Loading in Bone Mechanobiology
10. Section III. Experimental Methods
11. Chapter 3.1. Mechanobiology in Soft Tissue Engineering
12. Chapter 3.2. Intracellular Force Measurements in Live Cells With Förster Resonance Energy Transfer–Based Molecular Tension Sensors
13. Section IV. Computational Simulations in Mechanobiology
14. Chapter 4.1. Multiscale Models Coupling Chemical Signaling and Mechanical Properties for Studying Tissue Growth
15. Chapter 4.2. Computational Morphogenesis of Embryonic Bone Development: Past, Present, and Future

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