Mitochondrial Intoxication Marcos Roberto De Oliveira

Mitochondrial Intoxication – Ebook Instant Download/Delivery ISBN(s): 9780323884624,0323884628

Product details:

• ISBN-10 ‏ : ‎ 0323884628
• ISBN-13 ‏ : ‎ 978-0323884624
• Author: Marcos Roberto de Oliveira

Mitochondrial Intoxication explores the effects toxic molecules can have upon mitochondrial physiology in the human body. Each chapter is dedicated to a specific toxicant, including pollutants, food additives, illicit and pharmaceutical drugs, and heavy metals. This book considers the implications and impact these have upon mitochondria and the diseases that can result from dysfunction and impairment in the human body. Furthermore, the book provides an overview of mitochondrial physiology and assesses the advances and challenges in testing mitochondrial toxicity. Case studies exploring mitochondrial intoxication in pregnancy and in the geriatric population are also included.

Table contents:

1: Mitochondrial physiology: An overview

2: Molecular markers of mitochondrial intoxication

3: Drug-induced mitochondrial impairment: Mechanisms and testing systems

4: Clinical consequences of drug-induced mitochondrial dysfunction

5: Challenges in mitochondrial profiling during pre-clinical studies

6: Mitochondrial dysfunction and underlying molecular mechanisms in acrylamide-induced toxicity

7: The effects of air pollution toxicants on the mitochondria

8: Mitochondrial toxicity of aflatoxin B1

9: The effects of alcohol abuse against the mitochondria: Functional consequences for liver, muscle, and the brain

10: The effect of aluminum on mitochondrial dysfunctions

11: Discovery of amiodarone mitochondrial toxicity in liver and beyond

12: Ammonia

References
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