Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals 1st edition Sergej M. Ostojic

Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals 1st edition Sergej M. Ostojic – Ebook Instant Download/Delivery ISBN(s): 9780323902564,0323902561,9780323984522, 0323984525

Product details:

• ISBN 10:0323984525
• ISBN 13: 9780323984522
• Author: Sergej M. Ostojic

Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction.

Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food.

Table contents:

SECTION I

1. Nutritional Support in Mitochondrial Diseases: The State of the Art

2. Targeting Mitochondrial Dysfunction: Challenges and Opportunities

3. Impact of Mitointeractions On Health-Disease Responses to Diet

4. Mitochondrion at the Crossroads Between Nutrients and Epigenome

5. Inadequate Nutritional Intake in Mitochondrial Diseases

6. Nutritional Deficits Involved in Mitocondrial Damage in Critical Illness

SECTION II

7. Mitochondrial Response to Controlled Nutrition in Health and Disease

8. Diet Restriction-Induced Mitochondrial Signalling and Healthy Aging

9. Ketogenic Diets, Mitochondria, and Neurological diseases

10. Ferility Diet and Mitochondrial Function

11. Maternal Nutrient Modulation and Fetal Mitochondrial Gene Expression

12. Dietary Modulation and Mitochondrial DNA Damage

SECTION III

13. Vitamin E, Mitochondrial Dysfunction and Aging

14. The Role of B Vitamins in Protecting Mitochondrial Function

15. Triggering Mitochondrion-Dependent Necrosis by Fatty Acids

16. Dietary Lipids and Mitochondrial Gene Expression

17. Dietary EPA and DHA for Mitochondrial Biosynthesis and Dynamics

18. Supplemental Vitamin C for Mitochondrial Biogenesis in Health and Exercise

SECTION IV

19. Mitochondria-Targeted Antioxidants: Coezyme Q10, MitoQ and beyond

20. Flavonoids, Mitochondrial Enzymes and Heart Protection

21. Tea Polyphenols Stimulate Mt Bioenergetics in Cardiometabolic Diseases

22. Quercetin and Mitochondria: from Nutrition to Nanomedicine

23. N-acetylcysteine and Up-Regulation of Mitochondrial Biogenesis

24. Dietary Carnitine, Mitochondrial Function and Therapy

25. Creatine Monohydrate for Mitochondrial Nutrition

26. Benefits of Supplemental Arginine and Citrullne in MELAS syndrome

27. Nutraceuticals for Targeting NAD+ to Restore Mitochondrial Function

28. Curcumin for Protecting Mitochondria and Down Regulating Inflammation

29. Dietary Molecular Hydrogen for Mitochondrial Viability

30. Fucoxantin and Mitochondrial Uncoupling Protein-1 in Obesity

31. Rice Bran Extract for the Prevention of Mitochondrial Dysfunction

32. Dietary Modulators of Nuclear Factor Erythroid-2-Related Factor 2

33. Plant Silymarin Affects Mitochondrial Integrity in Stress Conditions

34. Alternative Respiratory Chain Enzymes: Therapeutic Potential and Possible Pitfalls

35. New Mitochondria Permeability Transition Pore Inhibitor Based on Dietary Gallic Acid

36. Plant-Derived Compounds, Vitagens, and Mitochondrial Function

37. Buckwheat Trypsin Inhibitor (rBTI): A Novel Nutrceutical for Mitochondrial Homeostasis in Age-Related Conditions

38. Nutraceutical Effects of Indian Gooseberry on Mitochondria-Mediated Cellular Damage

39. 5-Heptadecylresorcinol from Whol Grain Rye for Mitochondrial Bioactivities

40. Combined Nutraceutical Therapy for Mitochondrial Cytopathies

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