Oxford Handbook of Evolutionary Medicine 1st Edition Martin Brüne

Oxford Handbook of Evolutionary Medicine – Ebook Instant Download/Delivery ISBN(s): 9780198789666,0198789661,2018944186

Product details:

• ISBN-10 ‏ : ‎ 0198789661
• ISBN-13 ‏ : ‎ 978-0198789666
• Author(s): Martin Brüne, Wulf Schiefenhövel

Medicine is grounded in the natural sciences, among which biology stands out with regard to the understanding of human physiology and conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system to find adequate responses.

In addition, many adaptations to past ecologies have turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. In addition, depression, anxiety and other psychiatric conditions add to the list.

Table contents:

Part I: General Principles

1. Core Principles for Evolutionary Medicine, Randolph Nesse

2. Cellular Signalling Systems, Diana Le Duc & Torsten Schoneberg

3. Genetics and Epigenetics, Paul Ewald & Holly Swain Ewald

4. Growth and Development, Robin Miriam Bernstein & Barry Bogin

5. Senescence and Ageing, Xiaqing Zhao & Daniel Promislow

6. Nutrition, Body Composition, Physical Activity, and Energy Expenditure, Ann Caldwell, S. Boyd Eaton & Melvin Konner

Part II: Specific Systems

7. Musculoskeletal System, Martin Hausler, Nicole Bender, Lafi Aldakak, Francesco M. Galassi, Patrick Eppenberger, Maciej Henneberg & Frank Ruhli

8. Skin and Integument, Mark Hill

9. Haematopoetic System, Eric Pietras & James DeGregori

10. Immune System, Graham Rook

11. Cardiovascular System, Kevin S. Shah, Kalyanam Shivkumar, Mehdi Nojo & Barbara Natterson-Horowitz

12. Respiratory System, Olga Carvalho & John Maina

13. Digestive System, John Furness, Eve K. Boyle, Josiane Fakhry, Joanna Gajewski & Linda J Fothergill

14. Excretory System, Paola Romagnani & Hans-Joachim Anders

15. Endocrinology, Richard Bribiescas16. Sexuality, Reproduction, and Birth, Wulf Schiefenhovel & Wenda Trevathan

17. Brain, Spinal Cord and Sensory Systems, Martin Brune

18. The Future of Medicine, Wulf Schiefenhovel & Martin Brune

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