Oxford Textbook of Cancer Biology 1st Edition

Oxford Textbook of Cancer Biology 1st Edition – Ebook Instant Download/Delivery ISBN(s): 9780198779452,0198779453,2018960018, 9780191084874, 0191084875

Product details:

• ISBN 10: 0191084875
• ISBN 13: 9780191084874
• Author: Francesco Pezzella, Mahvash Tavassoli, David J Kerr

The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today’s cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Table contents:

Section I The multicellular organism

1. The multicellular organism and cancer

2. DNA repair and genome integrity

3. Evolution and cancer

Section II The aetiology of cancer

4. Genetics and genetic instability in cancer

5. Epigenetics

6. Viral carcinogenesis—an overview

7. Chemical carcinogens

8. Radiation as a carcinogen

Section III How the cancer cell works

9. Growth factors and associated signalling pathways in tumour progression and in cancer treatment

10. Hormones and cancer

11. Oncogenesis and tumour suppression

12. The signalling pathways in cancer

13. Cell cycle control

14. Cancer and cell death

15. Telomerase and immortalization

16. Cancer metabolism

17. Chaperones and protein quality control in the neoplastic process

18. Oxygen and cancer: The response to hypoxia

19. Invasion, metastasis, and tumour dormancy

20. Cancer stem cells

Section IV Cancer microenvironment

21. Cancer-associated stroma

22. Blood vessels and cancer

23. Cancer immunology

Section V Global vision of cancer

24. Molecular profiling in cancer research and personalized medicine

25. Proteomics and metabolomics applications in cancer biology

26. Cancer systems biology: From molecular profiles to pathways, signalling networks, and therapeutic vulnerabilities

27. Cancer biology through immunohistology

Section VI The biology of cancer treatment

28. Principles of chemotherapy

29. Immunotherapy and tumour resistance to immune-mediated control and elimination

30. Biological effect of radiotherapy on cancer cells

Section VII Conclusions

31. Benign tumours: The forgotten neoplasms

32. Conclusions: Cancer biology, a moveable feast

People also search:

oxford textbook of cancer biology pdf

cancer biology textbook

cancer biology book

biology oxford textbook pdf

quizlet on biology