Post-transcriptional Gene Regulation in Human Disease 1st Edition

Post-transcriptional Gene Regulation in Human Disease 1st Edition – Ebook Instant Download/Delivery ISBN(s): 9780323913058,9780323914246,0323913059,0323914241

Product details:

• ISBN-10: 0323914241
• ISBN-13: 9780323914246
• Author: Buddhi Jain, Shyamal Goswami and Tapan Sharma

Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.

Table contents:

Chapter 1. Regulation of gene expression in mammals: an overview

Chapter 2. Post-transcriptional gene regulation: an overview

Chapter 3. Methods to study post-transcriptional regulation of gene expression

Chapter 4. Epigenetic regulation of post-transcriptional machinery

Chapter 5. Post-transcriptional regulation: a less explored territory in the world of neurodegenerative diseases

Chapter 6. Role of post-transcriptional gene regulation in hematological malignancies

Chapter 7. Post-transcriptional gene regulation in solid tumors

Chapter 8. A comprehensive view of the prostate cancer metastasis and role of androgen receptor splice variants

Chapter 9. Post-transcriptional gene regulation in Cardiorenal syndrome

Chapter 10. Noncoding RNAs as modulators of post-transcriptional changes and their role in CVDs

Chapter 11. microRNAs as critical regulators in heart development and diseases

Chapter 12. MicroRNA regulation in autoimmune diseases

Chapter 13. Post-transcriptional regulation of inflammatory disorder

Chapter 14. Post-transcriptional gene regulation in metabolic syndrome

Chapter 15. Post-transcriptional regulation of HIV-1 gene expression: role of viral and host factors

Chapter 16. Post-transcriptional regulation of gene expression in Entamoeba histolytica

Chapter 17. Post-transcriptional regulation of gene expression in human malaria parasite Plasmodium falciparum

Chapter 18. Hepcidin-induced degradation of iron exporter ferroportin determines anemia of chronic diseases

Chapter 19. Post-transcriptional regulation of genes and mitochondrial disorder

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