Post-transcriptional Gene Regulation in Human Disease 1st Edition – Ebook Instant Download/Delivery ISBN(s): 9780323913058,9780323914246,0323913059,0323914241
Product details:
- ISBN-10: 0323914241
- ISBN-13: 9780323914246
- Author: Buddhi Jain, Shyamal Goswami and Tapan Sharma
Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.
Table contents:
Chapter 1. Regulation of gene expression in mammals: an overview
Chapter 2. Post-transcriptional gene regulation: an overview
Chapter 3. Methods to study post-transcriptional regulation of gene expression
Chapter 4. Epigenetic regulation of post-transcriptional machinery
Chapter 5. Post-transcriptional regulation: a less explored territory in the world of neurodegenerative diseases
Chapter 6. Role of post-transcriptional gene regulation in hematological malignancies
Chapter 7. Post-transcriptional gene regulation in solid tumors
Chapter 8. A comprehensive view of the prostate cancer metastasis and role of androgen receptor splice variants
Chapter 9. Post-transcriptional gene regulation in Cardiorenal syndrome
Chapter 10. Noncoding RNAs as modulators of post-transcriptional changes and their role in CVDs
Chapter 11. microRNAs as critical regulators in heart development and diseases
Chapter 12. MicroRNA regulation in autoimmune diseases
Chapter 13. Post-transcriptional regulation of inflammatory disorder
Chapter 14. Post-transcriptional gene regulation in metabolic syndrome
Chapter 15. Post-transcriptional regulation of HIV-1 gene expression: role of viral and host factors
Chapter 16. Post-transcriptional regulation of gene expression in Entamoeba histolytica
Chapter 17. Post-transcriptional regulation of gene expression in human malaria parasite Plasmodium falciparum
Chapter 18. Hepcidin-induced degradation of iron exporter ferroportin determines anemia of chronic diseases
Chapter 19. Post-transcriptional regulation of genes and mitochondrial disorder
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