(EBook PDF) Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development 1st edition by Michal Hicks, Paul Ferguson 0323884881 9780323884884 full chapters

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Product details:

ISBN-10:   0323884881

ISBN-13 :  9780323884884

Author :  Michal Hicks, Paul Ferguson

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable “go-to” reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods.

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development 1st Table of contents:

Chapter 1: Evolution of packed column SFC as a greener analytical tool for pharmaceutical analysis

Chapter 2: Application space for SFC in pharmaceutical drug discovery and development

Chapter 3: Selection of SFC stationary and mobile phases

Chapter 4: Measurements of drugs and metabolites in biological matrices using SFC and SFE-SFC-MS

Chapter 5: Synthetic chemistry screening for robust analysis and purification from discovery through to development

Chapter 6: Application of preparative SFC in the pharmaceutical industry

Chapter 7: Method development approaches for small-molecule analytes

Chapter 8: Application of SFC for the characterization of formulated drug products

Chapter 9: Expanding the boundaries of SFC: Analysis of biomolecules

Chapter 10: Different detectors used with SFC

Chapter 11: SFC in GMP testing and quality control of medicinal drug products

Chapter 12: Best practices and instrumental troubleshooting for successful SFC methods

Chapter 13: The state-of-the-art and future perspectives for SFC

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Practical Application,Supercritical Chromatography,Pharmaceutical Research,Michal Hicks,Paul Ferguson