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Preadjusted Edgewise Fixed Orthodontic Appliances. Farhad B Naini, Daljit S Gill, Wiley-Blackwell 2022-TLS – Ebook Instant Download/Delivery ISBN(s): 9780128210444,0128210443

 

Product details:

• ISBN-10 ‏ : ‎ 0128210443
• ISBN-13 ‏ : ‎ 978-0128210444
• Author: Brad Bolon

Haschek and Rousseaux’s Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters.

Completely revised with a number of new chapters, Volume 1, “Principles and the Practice of Toxicologic Pathology,” covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses “Toxicologic Pathology in Safety Assessment” and “Environmental Toxicologic Pathology”. These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of “Target Organ Toxicity”, emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.

Table contents:

Chapter 1. Toxicologic Pathology: An Introduction

Part 1. Principles of Toxicologic Pathology
Chapter 2. Biochemical and Molecular Basis of Toxicity

Chapter 3. ADME Principles in Small Molecule Drug Discovery and Development: An Industrial Perspective

Chapter 4. Biotherapeutics ADME and PK/PD Principles

Chapter 5. Principles of Pharmacodynamics and Toxicodynamics

Chapter 6. Morphologic Manifestations of Toxic Cell Injury

Chapter 7. The Role of Pathology in Evaluation of Reproductive, Developmental, and Juvenile Toxicity

Chapter 8. Carcinogenesis: Mechanisms and Evaluation

Part 2. Methods in Toxicologic Pathology
Chapter 9. Basic Approaches in Anatomic Toxicologic Pathology

Chapter 10. Clinical Pathology in Nonclinical Toxicity Testing

Chapter 11. Special Techniques in Toxicologic Pathology

Chapter 12. Digital Pathology and Tissue Image Analysis

Chapter 13. In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models

Chapter 14. Biomarkers: Discovery, Qualification, and Application

Chapter 15. Toxicogenomics: A Primer for Toxicologic Pathologists

Chapter 16. Experimental Design and Statistical Analysis for Toxicologic Pathologists

Part 3. Animal and Alternative Models in Toxicologic Research
Chapter 17. Animal Models in Toxicologic Research: Rodents

Chapter 18. Animal Models in Toxicologic Research: Rabbit

Chapter 19. Animal Models in Toxicologic Research: Dog

Chapter 20. Animal Models in Toxicologic Research: Pig

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