(EBook PDF) Rang and Dale’s Pharmacology Flash Cards 2nd Edition by James Ritter, Emma Robinson, James Fullerton, Rod Flower, Graeme Henderson, Yoon Kong Loke 0702074454 9780702074455 full chapters

Rang & Dale’s Pharmacology Flash Cards 2nd Edition by James M. Ritter, Emma Robinson, James Fullerton, Rod J. Flower, Graeme Henderson, Yoon Kong Loke – Ebook PDF Instant Download/DeliveryISBN:  0702074454, 9780702074455 

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ISBN-10 :  0702074454

ISBN-13 :  9780702074455

Author: James M. Ritter, Emma Robinson, James Fullerton, Rod J. Flower, Graeme Henderson, Yoon Kong Loke

Rang & Dale’s Pharmacology

Rang & Dale’s Pharmacology Flash Cards 2nd Table of contents:

1 What is pharmacology?
What Is a Drug?
Origins and Antecedents
Pharmacology in the 20Th and 21St Centuries
References and Further Reading
2 How drugs act
Introduction
Protein Targets for Drug Binding
Desensitisation and Tolerance
Quantitative Aspects of Drug–Receptor Interactions
The Nature of Drug Effects
References and Further Reading
3 How drugs act
Protein Targets for Drug Action
Receptor Proteins
Ion Channels as Drug Targets
Control of Receptor Expression
Receptors and Disease
References and Further Reading
4 How drugs act
Regulation of Intracellular Calcium
Excitation
Muscle Contraction
Release of Chemical Mediators
Epithelial Ion Transport
References and Further Reading
5 How drugs act
Introduction
Protein and Oligonucleotide Biopharmaceuticals
Oligonucleotides
Gene Therapy
Safety and Societal Issues
Therapeutic Applications
Concluding Remarks
References and Further Reading
6 Cell proliferation, apoptosis, repair and regeneration
Cell Proliferation
Angiogenesis
Apoptosis and Cell Removal
Pathophysiological Implications
Therapeutic Prospects
References and Further Reading
7 Cellular mechanisms
Introduction
The Innate Immune Response
The Adaptive Immune Response
Systemic Responses in Inflammation
References and Further Reading
8 Method and measurement in pharmacology
Bioassay
Animal Models of Disease
Pharmacological Studies in Humans
Clinical Trials
References and Further Reading
9 Absorption and distribution of drugs
Introduction
Physical Processes Underlying Drug Disposition
Drug Absorption and Routes of Administration
Distribution of Drugs in the Body
Special Drug Delivery Systems
References and Further Reading
10 Drug metabolism and elimination
Introduction
Drug and Metabolite Excretion
References and Further Reading
11 Pharmacokinetics
Introduction: Definition and Uses of Pharmacokinetics
Drug Elimination Expressed as Clearance
Single-Compartment Model
More Complicated Kinetic Models
Population Pharmacokinetics
Limitations of Pharmacokinetics
References and Further Reading
12 Individual variation, pharmacogenomics and personalised medicine
Introduction
Epidemiological Factors and Inter-Individual Variation of Drug Response
Genetic Variation in Drug Responsiveness
Therapeutic Drugs and Clinically Available Pharmacogenomic Tests
Conclusions
References and Further Reading
Section 2 Chemical mediators
13 Chemical mediators and the autonomic nervous system
Historical Aspects
The Autonomic Nervous System
Some General Principles of Chemical Transmission
Basic Steps in Neurochemical Transmission: Sites of Drug Action
References and Further Reading
14 Cholinergic transmission
Muscarinic and Nicotinic Actions of Acetylcholine
Acetylcholine Receptors
Nicotinic Receptors
Physiology of Cholinergic Transmission
Effects of Drugs on Cholinergic Transmission
References and Further Reading
15 Noradrenergic transmission
Catecholamines
Classification of Adrenoceptors
Physiology of Noradrenergic Transmission
Drugs Acting on Noradrenergic Transmission
References and Further Reading
16 5-Hydroxytryptamine and the pharmacology of migraine
5-Hydroxytryptamine
Migraine and Other Clinical Conditions in Which 5-HT Plays a Role
References and Further Reading
17 Purines
Introduction
Purinergic Receptors
Adenosine as a Mediator
ADP as a Mediator
ATP as a Mediator
Future Prospects
References and Further Reading
18 Local hormones 1
Introduction
What Is a ‘Mediator’?
Histamine
Eicosanoids
Leukotrienes
Other Important Fatty Acid Derivatives
Platelet-Activating Factor
Concluding Remarks
References and Further Reading
19 Local hormones 2
Introduction
General Principles of Protein and Peptide Pharmacology
Biosynthesis and Regulation of Peptides
Bradykinin
Neuropeptides
Cytokines
Proteins and Peptides That Down-Regulate Inflammation
Concluding Remarks
References and Further Reading
20 Cannabinoids
Plant-Derived Cannabinoids and Their Pharmacological Effects
Cannabinoid Receptors
Endocannabinoids
Synthetic Cannabinoids
Clinical Applications
References and Further Reading
21 Nitric oxide and related mediators
Introduction
Biosynthesis of Nitric Oxide and Its Control
Degradation and Carriage of Nitric Oxide
Effects of Nitric Oxide
Therapeutic Aspects
Clinical Conditions in Which Nitric Oxide May Play A Part
Related Mediators
References and Further Reading
Section 3 Drugs affecting major organ systems
22 The heart
Introduction
Physiology of Cardiac Function
Autonomic Control of the Heart
Cardiac Natriuretic Peptides
Ischaemic Heart Disease
Drugs That Affect Cardiac Function
References and Further Reading
23 The vascular system
Introduction
Vascular Structure and Function
Control of Vascular Smooth Muscle Tone
Vasoactive Drugs
Clinical Uses of Vasoactive Drugs
References and Further Reading
24 Atherosclerosis and lipoprotein metabolism
Introduction
Atherogenesis
Lipoprotein Transport
Prevention of Atheromatous Disease
Lipid-Lowering Drugs
References and Further Reading
25 Haemostasis and thrombosis
Introduction
Blood Coagulation
Drugs That Act on the Coagulation Cascade
Platelet Adhesion and Activation
Fibrinolysis (Thrombolysis)
References and Further Reading
26 Haematopoietic system and treatment of anaemia
Introduction
The Haematopoietic System
Types of Anaemia
Haematinic Agents
Haematopoietic Growth Factors
Haemolytic Anaemia
References and Further Reading
27 Anti-inflammatory and immunosuppressant drugs
Introduction
Cyclo-Oxygenase Inhibitors
Antirheumatoid Drugs
Anticytokine Drugs and Other Biopharmaceuticals
Drugs Used in Gout
Antagonists of Histamine
Possible Future Developments IN ANTIINFLAMMATORY THERAPY
References and Further Reading
28 Skin
Introduction
Structure of Skin
Common Diseases of the Skin
Drugs Acting on Skin
Principal Drugs Used in Skin Disorders
Agents Acting by Other Mechanisms
Concluding Remarks
References and Further Reading
29 Respiratory system
The Physiology of Respiration
Pulmonary Disease and Its Treatment
References and Further Reading
30 The kidney and urinary system
Introduction
Outline of Renal Function
The Structure and Function of the Nephron
Drugs Acting on the Kidney
Drugs That Alter the pH of the Urine
Drugs That Alter the Excretion of Organic Molecules
Drugs Used in Renal Failure
Drugs Used in Urinary Tract Disorders
References and Further Reading

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